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decon-eqtl  (Decon Laboratories)

 
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    Decon Laboratories decon-eqtl
    Decon Eqtl, supplied by Decon Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/decon-eqtl/product/Decon Laboratories
    Average 90 stars, based on 1 article reviews
    decon-eqtl - by Bioz Stars, 2026-04
    90/100 stars

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    ( A ) Total <t>SCZ</t> <t>GWAS</t> <t>heritability</t> ( h 2) explained by eQTLs. ( B ) SCZ GWAS heritability enrichment in eQTLs. Enrichment = h 2/number of SNPs in each eQTL category.
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    ( A ) Illustration of decon-eQTL mapping. ( B ) Number of <t>decon-eQTLs</t> identified in different cell types at FDR < 0.05 in the permutation test. ( C ) Pi 1 statistics of decon-eQTLs in BrainGVEX decon-eQTLs and ( D ) eQTLs from snRNA-seq study of Bryois et al. . For calculating Pi 1 statistics, decon-eQTLs from ROSMAP were used as testing data, and eQTLs from BrainGVEX and Bryois et al. were used as references. ( E ) Comparison of decon-eQTLs and bulk tissue eQTLs. The top barplot shows the Pi 1 values of decon-eQTLs (testing data) in bulk tissue eQTLs (reference). The bottom plot shows the intersections between decon-eQTLs and bulk tissue eQTLs, as well as intersections of decon-eQTLs across various cell types.
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    ( A ) Illustration of decon-eQTL mapping. ( B ) Number of <t>decon-eQTLs</t> identified in different cell types at FDR < 0.05 in the permutation test. ( C ) Pi 1 statistics of decon-eQTLs in BrainGVEX decon-eQTLs and ( D ) eQTLs from snRNA-seq study of Bryois et al. . For calculating Pi 1 statistics, decon-eQTLs from ROSMAP were used as testing data, and eQTLs from BrainGVEX and Bryois et al. were used as references. ( E ) Comparison of decon-eQTLs and bulk tissue eQTLs. The top barplot shows the Pi 1 values of decon-eQTLs (testing data) in bulk tissue eQTLs (reference). The bottom plot shows the intersections between decon-eQTLs and bulk tissue eQTLs, as well as intersections of decon-eQTLs across various cell types.
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    Image Search Results


    ( A ) Total SCZ GWAS heritability ( h 2) explained by eQTLs. ( B ) SCZ GWAS heritability enrichment in eQTLs. Enrichment = h 2/number of SNPs in each eQTL category.

    Journal: Science Advances

    Article Title: Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data

    doi: 10.1126/sciadv.adh2588

    Figure Lengend Snippet: ( A ) Total SCZ GWAS heritability ( h 2) explained by eQTLs. ( B ) SCZ GWAS heritability enrichment in eQTLs. Enrichment = h 2/number of SNPs in each eQTL category.

    Article Snippet: Decon-eQTLs of all cell types were enriched for SCZ GWAS heritability ( P value < 0.05; ).

    Techniques:

    ( A ) Illustration of decon-eQTL mapping. ( B ) Number of decon-eQTLs identified in different cell types at FDR < 0.05 in the permutation test. ( C ) Pi 1 statistics of decon-eQTLs in BrainGVEX decon-eQTLs and ( D ) eQTLs from snRNA-seq study of Bryois et al. . For calculating Pi 1 statistics, decon-eQTLs from ROSMAP were used as testing data, and eQTLs from BrainGVEX and Bryois et al. were used as references. ( E ) Comparison of decon-eQTLs and bulk tissue eQTLs. The top barplot shows the Pi 1 values of decon-eQTLs (testing data) in bulk tissue eQTLs (reference). The bottom plot shows the intersections between decon-eQTLs and bulk tissue eQTLs, as well as intersections of decon-eQTLs across various cell types.

    Journal: Science Advances

    Article Title: Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data

    doi: 10.1126/sciadv.adh2588

    Figure Lengend Snippet: ( A ) Illustration of decon-eQTL mapping. ( B ) Number of decon-eQTLs identified in different cell types at FDR < 0.05 in the permutation test. ( C ) Pi 1 statistics of decon-eQTLs in BrainGVEX decon-eQTLs and ( D ) eQTLs from snRNA-seq study of Bryois et al. . For calculating Pi 1 statistics, decon-eQTLs from ROSMAP were used as testing data, and eQTLs from BrainGVEX and Bryois et al. were used as references. ( E ) Comparison of decon-eQTLs and bulk tissue eQTLs. The top barplot shows the Pi 1 values of decon-eQTLs (testing data) in bulk tissue eQTLs (reference). The bottom plot shows the intersections between decon-eQTLs and bulk tissue eQTLs, as well as intersections of decon-eQTLs across various cell types.

    Article Snippet: The cell-type eQTLs identified with deconvoluted gene expressions were named deconvolution eQTLs (decon-eQTLs).

    Techniques: Comparison

    ( A ) Total SCZ GWAS heritability ( h 2) explained by eQTLs. ( B ) SCZ GWAS heritability enrichment in eQTLs. Enrichment = h 2/number of SNPs in each eQTL category.

    Journal: Science Advances

    Article Title: Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data

    doi: 10.1126/sciadv.adh2588

    Figure Lengend Snippet: ( A ) Total SCZ GWAS heritability ( h 2) explained by eQTLs. ( B ) SCZ GWAS heritability enrichment in eQTLs. Enrichment = h 2/number of SNPs in each eQTL category.

    Article Snippet: The cell-type eQTLs identified with deconvoluted gene expressions were named deconvolution eQTLs (decon-eQTLs).

    Techniques: